D.Phil Thesis

My D. Phil. research with Professor Ole Paulsen was focused on early cortical development and how sensory experiences refine synaptic circuitry of mammalian barrel cortex. The main focus was to investigate the expression and function of presynaptic NMDA receptors and how they control timing- and pattern-dependent synaptic plasticity in the barrel cortex during early postnatal development. Title of my D.Phil thesis was "Timing- and Pattern-dependent Long-term Depression during Mammalian Cortical Development" (Thesis Examiners: Professor Kevin Fox and Dr. Colin Akerman) and specific projects I was involved with were:

* Developmental profile and NMDA receptor subtype-dependence of STDP during mouse barrel cortex development

* Presynaptic NMDA receptors and LTD mechanisms in the barrel cortex

* Optogenetic probing of astrocytic regulation of synaptic plasticity

* Whisker stimulation induced plasticity in vivo in the mouse barrel cortex

You can read my D.Phil abstract here. Please email me if you want a copy of my thesis.